Publications
Representative publications:
Prior Fc Receptor activation primes macrophages for increased sensitivity to IgG via long term and short term mechanisms. Bond A, Fiaz S, Rollins K, Nario JEQ, Snyder ET, Atkins DJ, Rosen SJ, Granados A, Dey SS, Wilson MZ, Morrissey MA. Dev Cell. 2024 doi: 10.1016/j.devcel.2024.07.017
About this paper: Interview with Annalise on NIH Directors Blog.
An appetizer can stimulate immune cells’ appetite, a boon for cancer treatments
Tight nanoscale clustering of Fcγ-receptors using DNA origami promotes phagocytosis. Kern N, Dong R, Douglas SM, Vale RD, Morrissey MA. eLife 2020 Jun 3. doi: 10.7554/eLife.68311.
About this paper: Prelight by NYU graduate students here! "Can Macrophages Count?" eLife digest here!
CD47 ligation repositions the inhibitory receptor SIRPA to suppress integrin activation and phagocytosis. Morrissey MA, Kern N, Vale RD. Immunity. 2020 Aug 8. doi: 10.1016/j.immuni.2020.07.008.
Chimeric antigen receptors that trigger phagocytosis. Morrissey MA*, Williamson AP*, Steinbach AM, Roberts EW, Kern N, Headley MB, Vale RD. eLife. 2018 Jun 4;7:e36688. doi: 10.7554/eLife.36688. PMID: 29862966.
All publications:
Biochemical and biophysical mechanisms macrophages use to tune phagocytic appetite. Bond A, Morrissey MA. J Cell Sci. 2025 Jan 1;138(1):JCS263513. doi: 10.1242/jcs.263513. Epub 2025 Jan 3. Review.
Prior Fc Receptor activation primes macrophages for increased sensitivity to IgG via long term and short term mechanisms. Bond A, Fiaz S, Rollins K, Nario JEQ, Snyder ET, Atkins DJ, Rosen SJ, Granados A, Dey SS, Wilson MZ, Morrissey MA. Dev Cell. 2024 doi: 10.1016/j.devcel.2024.07.017
About this paper: Interview with Annalise on NIH Directors Blog.
An appetizer can stimulate immune cells’ appetite, a boon for cancer treatments
A genome-wide screen links peroxisome regulation with Wnt signaling through RNF146 and TNKS/2. Vu JT, Tavasoli KU, Sheedy CJ, Chowdhury, SP, Mandjikian L, Bacal J, Morrissey MA, Richardson CD, Gardner BM. J Cell Biol. 2024 Oct 7;223(10):e202312069. doi: 10.1083/jcb.202312069.
Engineering water exchange is a safe and effective method for magnetic resonance imaging in diverse cell types. Miller ADC, Chowdhury SP, Hanson HW, Linderman SK, Ghasemi HI, Miller WD, Morrissey MA, Richardson CD, Gardner BM, Mukherjee A.J Biol Eng. 2024 Apr 22;18(1):30. doi: 10.1186/s13036-024-00424-5.
Hyperactive Rac stimulates cannibalism of living target cells and enhances CAR-M-mediated cancer cell killing. Mishra AK, Rodriguez M Torres AY, Smith M, Rodriguez A, Bond A, Morrissey MA, Montell DJ. PNAS 2023 Dec 18. doi: 10.1073/pnas.2310221120
About this paper: When Bad Cells go Good ; Cannibal Cells Inspire Cancer treatments
Leveraging DNA Origami to Study Phagocytosis. Miller WD, Kern N, Douglas SM, Morrissey MA. Methods Mol Biol. 2023 April 28. doi: 10.1007/978-1-0716-3135-5_19.
Tight nanoscale clustering of Fcγ-receptors using DNA origami promotes phagocytosis. Kern N, Dong R, Douglas SM, Vale RD, Morrissey MA. eLife 2020 Jun 3. doi: 10.7554/eLife.68311.
About this paper: Prelight by NYU graduate students here! "Can Macrophages Count?" eLife digest here!
CD47 ligation repositions the inhibitory receptor SIRPA to suppress integrin activation and phagocytosis. Morrissey MA, Kern N, Vale RD. Immunity. 2020 Aug 8. doi: 10.1016/j.immuni.2020.07.008.
Chimeric antigen receptors that trigger phagocytosis. Morrissey MA*, Williamson AP*, Steinbach AM, Roberts EW, Kern N, Headley MB, Vale RD. eLife. 2018 Jun 4;7:e36688. doi: 10.7554/eLife.36688. PMID: 29862966.
SPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement Membrane. Morrissey MA, Jayadev R, Miley GR, Blebea CA, Chi Q, Ihara S, Sherwood DR. PLoS Genet. 2016 Feb 29;12(2):e1005905. doi: 10.1371/journal.pgen.1005905. eCollection 2016 Feb. PMID: 26926673
B-LINK: a hemicentin, plakin, and integrin-dependent adhesion system that links tissues by connecting adjacent basement membranes. Morrissey MA, Keeley DP, Hagedorn EJ, McClatchey STH, Chi Q, Hall DH, Sherwood DR. Dev Cell. 2014 Nov 10;31(3):319-331. doi: 10.1016/j.devcel.2014.08.024. Epub 2014 Oct 23. PMID: 25443298