Prior Fc Receptor activation primes macrophages for increased sensitivity to IgG via long term and short term mechanisms. Bond A, Fiaz S, Rollins K, Nario JEQ, Rosen SJ, Granados A, Wilson MZ, Morrissey MA. bioRxiv. 2023 Nov 14. doi: 10.1101/2023.11.14.567059

     About this paper: Interview with Annalise on NIH Directors Blog.


Peer reviewed:

Hyperactive Rac stimulates cannibalism of living target cells and enhances CAR-M-mediated cancer cell killing. Mishra AK, Rodriguez M Torres AY, Smith M, Rodriguez A, Bond A, Morrissey MA, Montell DJ. PNAS 2023 Dec 18. doi: 10.1073/pnas.2310221120

     About this paper: When Bad Cells go Good

Leveraging DNA Origami to Study Phagocytosis. Miller WD, Kern N, Douglas SM, Morrissey MA. Methods Mol Biol. 2023 April 28. doi: 10.1007/978-1-0716-3135-5_19.

Tight nanoscale clustering of Fcγ-receptors using DNA origami promotes phagocytosis. Kern N, Dong R, Douglas SM, Vale RD, Morrissey MA. eLife 2020 Jun 3. doi: 10.7554/eLife.68311. 

     About this paper: Prelight by NYU graduate students here! "Can Macrophages Count?" eLife digest here!


Meghan's postdoc work:

CD47 ligation repositions the inhibitory receptor SIRPA to suppress integrin activation and phagocytosis. Morrissey MA, Kern N, Vale RD. Immunity. 2020 Aug 8. doi: 10.1016/j.immuni.2020.07.008.  

Chimeric antigen receptors that trigger phagocytosisMorrissey MA*, Williamson AP*, Steinbach AM, Roberts EW, Kern N, Headley MB, Vale RD. eLife. 2018 Jun 4;7:e36688. doi: 10.7554/eLife.36688. PMID: 29862966. 

Meghan's graduate work:

SPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement Membrane. Morrissey MA, Jayadev R, Miley GR, Blebea CA, Chi Q, Ihara S, Sherwood DR. PLoS Genet. 2016 Feb 29;12(2):e1005905. doi: 10.1371/journal.pgen.1005905. eCollection 2016 Feb. PMID: 26926673

B-LINK: a hemicentin, plakin, and integrin-dependent adhesion system that links tissues by connecting adjacent basement membranes. Morrissey MA, Keeley DP, Hagedorn EJ, McClatchey STH, Chi Q, Hall DH, Sherwood DR. Dev Cell. 2014 Nov 10;31(3):319-331. doi: 10.1016/j.devcel.2014.08.024. Epub 2014 Oct 23. PMID: 25443298